https://www.ibiology.org/human-disease/leptin/ Talk Overview: Obesity is a highly heritable medical problem, with 70-80% of variants in body weight clarified by hereditary elements. In the 1990s, Jeffrey Friedman and also his colleagues were the first to show the hereditary basis for obesity when they recognized as well as cloned leptin, a hormonal agent produced by fat tissue, as the responsible variable for maintaining regular body weight. Friedman's research study has actually played a major duty in our understanding of human excessive weight as well as the hormone path that manages food consumption. Speaker Biography: Jeffrey Friedman is a Professor at the Rockefeller University and a private investigator of the Howard Hughes Medical Institute. His work with leptin and also body weight guideline has been vital for our understanding of just how genetics control human weight problems. Friedman, a member of the National Academy of Sciences, has obtained numerous honors for his study, consisting of the Albert Lasker Basic Medical Research Award as well as the Shaw Prize permanently Sciences and Medicine.